Ankylosing spondylitis is a slow-moving disease where prevention comes first. Early symptoms of ankylosing spondylitis manifest as back pain and morning stiffness, mostly from indirect pain to persistent pain. Ankylosing spondylitis can be very harmful to patients. How to prevent and treat ankylosing spondylitis in daily life? The following is an introduction. AS is a systemic disease that can damage several organs, such as hypothermia, fatigue, loss of appetite, wasting, and anemia. Some patients have peripheral neuropathy of the lower extremities, with muscle pain and numbness in the lower extremities below the knee. About a quarter of patients have ocular iridocyclitis with ocular pain, photophobia and lacrimation. Patients with severe disease are associated with cardiac aortic valve lesions, conduction disturbances and pulmonary fibrosis. The main renal damages are IgA nephropathy and renal amyloidosis. Comprehensive treatment of ankylosing spondylitis is emphasized, and the goal of treatment is to control inflammation and relieve symptoms; maintain normal posture and prevent spinal joint deformities. Ankylosing spondylitis requires early, long-term, or even lifelong treatment, and patients should have a proper understanding of their disease. Proper walking, good sleep posture and lumbar and abdominal exercises can maintain joint flexibility, and breathing exercises and swimming help maintain good lung function. A diet rich in protein and vitamins and low in animal fats should be taken, and calcium and cod liver oil should be added for those with combined osteoporosis. The most important and necessary test for the diagnosis of ankylosing spondylitis is to give the patient an MRI of the sacroiliac joint. If persistent or intermittent pain in the lumbosacral and hip areas occurs in adolescent males, accompanied by a feeling of stiffness in the lumbar region and limited bending and squatting, or if unexplained pain in the small joints of the heel, sternoclavicular, costal vertebrae, temporomandibular, stalk, and metatarsal phalanges occurs, one should think about whether or not he has ankylosing spondylitis and go to a regular hospital in a timely manner to avoid delaying the condition. Many patients are often not diagnosed until three or four years or even a decade after the onset of the disease. Therefore, it is important to raise awareness of the early symptoms of ankylosing spondylitis to achieve early diagnosis and early treatment to improve the cure rate and reduce the disability rate. The majority of patients with ankylosing spondylitis have an insidious onset, and early symptoms are often just stiffness or pain in the lower back, which is especially noticeable after turning over at night, getting up in the morning, or sitting or standing for a long time, and the stiffness and pain can partially improve after activity. In addition to the lumbosacral joints, the thoracic and cervical vertebrae can be involved. Some of the peripheral joints can also be involved and may be misdiagnosed as the first symptom, such as shoulder, foot, knee, hip, etc. A few small joints of the hand can be involved. In a few cases, the onset of the disease is acute, with severe pain in the lower back, hip and other affected joints, and the patient is often bedridden or even unable to turn over due to pain. In the late stage of the disease, all joints of the spine have been straightened and fixed, and the pain is not as pronounced and intense as in the early and middle stages, while joint stiffness and difficulty in movement are the main pain of the patient.