Ankylosing spondylitis (AS), is a systemic osteoarthropathy with chronic inflammation of the sacroiliac joints and spine. The characteristic pathological changes are tendon, ligament, and joint capsule bone attachment point inflammation. Late stage calcification and ossification of the involved areas culminate in spinal ankylosis. The disease was long misdiagnosed as a type of rheumatoid arthritis until the 1970s, when HLA-B27 (human leukocyte antigen) was found to be closely related to the development of the disease, which led to a new understanding and was gradually and clearly proposed as an independent disease different from rheumatoid arthritis. The prevalence of this disease in China is about 0.3%, mostly in people aged 10-30 years, with a peak incidence of 20-30 years. 40 years of age or older, less than 8 years of age, is rare; men are much more common than women, and the ratio of men to women is (2.5-4.1): 1. Statistics are not consistent around the world, such as 10:1 in Tianjin. Ankylosing spondylitis belongs to the “bone paralysis” and “kidney paralysis” in the scope of “paralysis” in Chinese medicine. The Su Wen. The theory of paralysis says: “Bone paralysis has not ceased, repeatedly feel the evil, internal surrender in the kidney …… kidney paralysis, good swelling, the tail to replace the heel, back to replace the head.” The symptoms of this disease are quite similar to the late stage of the disease. ”According to Chinese medicine, the disease is located in the lumbar spine and sacral joints, and the evil offends the tendons and bones, according to the theory of Chinese medicine, “the waist is the house of the kidneys”, the liver collects blood and the tendons, and the kidneys produce marrow and bones, so the pathology is closely related to the function of the liver and kidneys. Insufficient congenital endowment and improper regulation after birth result in deficiency of kidney essence, loss of bone nourishment, deficiency of liver yin, and loss of tendons and ligaments glory. The tendons and bones are weak and insufficient to resist external evil, which constitutes the internal basis of the disease. Wind, cold, and dampness attack the joints and tendons, resulting in disharmony between the camp and the body, pain due to paralysis of qi and blood, and unfavorable flexion and extension of the tendons and ligaments due to constriction. The paralysis obstructs the stagnation, which turns into heat and turbidity over time, and the stagnation and turbidity clump together, resulting in stiffness and straightness of the spine. The Qi meridian, which runs through the spine and belongs to the kidney, is the governor of the Yang meridians and plays an important role in warming and moistening the spinal joints and protecting them from external evil. Kidney deficiency by evil, will hurt its veins. Therefore, the disease follows the spine and up, even involving multiple joints or organs of the body, and because the disease is lingering and difficult to heal, delayed, often resulting in a deficiency of qi and blood throughout the body, depletion of positive qi, so ankylosing spondylitis is a deficiency of the real, deficiency of cold and heat mixed evidence.