Incidence rate of gallbladder cancer? The incidence of gallbladder cancer is about 2.5/100,000 in the United States, and there is no particularly accurate data in China. The prognosis of gallbladder cancer is very poor, with a median survival of about 10 months. Gallbladder cancer and laparoscopy Do patients with gallbladder cancer need to undergo routine laparoscopic exploration before surgery? Preoperative laparoscopy is not recommended for gallbladder cancer because the positive detection rate is low, but for stage T3 gallbladder cancer, laparoscopy may help to change the treatment plan. Surgical treatment of gallbladder cancer How to make surgical decision for patients with resectable tumor on open exploration but have developed peri-abdominal trunk and para-abdominal aortic lymph node metastasis? Is palliative resection or extensive lymph node dissection performed? Patients with peri-abdominal trunk and para-aortic lymph node metastases should be considered as IVb, and the prognosis is very poor, so surgical resection is not recommended. In fact, these metastases should be detected preoperatively by imaging, while avoiding patients to undergo the pain of open surgery.