Enlarged abdominal mesenteric lymph nodes in children may be a normal phenomenon or reactive enlargement caused by disease, mostly seen in mesenteric lymphadenitis, and it is recommended to seek medical attention in time to clarify the cause and then deal with it. Common causes and treatment are as follows: 1. Physiological phenomenon: children’s lymphatic system is in the process of development, lymph is in active stage, and reactive enlargement of lymph nodes can occur under the stimulation of various factors, which is a physiological phenomenon, and if it is not accompanied by other discomfort, such as abdominal pain, fever and other symptoms, no treatment is needed; 2. Disease phenomenon: germs and toxins produced by bacterial and viral infections will go through blood circulation and reach the distal ileal Lymphatic area, resulting in enlargement of the lymph nodes there, often causing pain around the umbilicus and small abdomen, pain lasting longer, hidden pain or spasmodic pain, accompanied by fever, vomiting, diarrhea and other symptoms in severe cases, common in mesenteric lymphadenitis, need to improve the abdominal ultrasound examination, under the guidance of the doctor should be cefixime, amoxicillin and other drug treatment, if there is a fever should be given acetaminophen to reduce temperature, usually It is necessary to take more rest and drink more water. In addition, a few children may be caused by malignant lymphoma, leukemia and other more serious diseases, should promptly consult a doctor to clarify the cause of treatment, if necessary, radiotherapy. Children need to develop good eating habits, drink more water, eat a light diet, do not eat spicy and stimulating food, eat regularly and do not overeat; they can exercise properly to increase their body resistance.