Patients with scleroderma can theoretically be treated with Hasinide, but Hasinide for the treatment of scleroderma is an over-the-counter medication and is recommended to be used in accordance with medical advice. Halcionide is a synthetic potent glucocorticoid, commonly available in solution, cream and film form, mostly used as a topical drug for the treatment of seborrheic dermatitis, contact dermatitis, eczema in infants and other glucocorticoid treatments are effective, so Halcionide can theoretically be used for the treatment of hardening of the skin in scleroderma. It should be noted that scleroderma also includes systemic sclerosis that not only invades the patient’s skin but also involves the internal organs. Patients with systemic sclerosis should take oral immunosuppressants such as cyclosporine and glucocorticosteroids such as prednisone to provide anti-inflammatory and immune-modulating treatments in addition to localized topical or intralesional glucocorticoid injections. It is contraindicated in patients who are hypersensitive to the drug components of Hasinide, in the presence of ulcerative lesions, acne, rosacea, and exudative dermatoses. Common adverse drug reactions after administration include tingling, burning sensation, temporary itching at the site of application. Note that large quantities of the drug over a large area or in a capped manner may result in more percutaneous absorption, and systemic reactions may occur, especially in younger children and infants. It is recommended that patients who need to use Hasinide treatment to the rheumatology and immunology department of the regular hospital for detailed consultation, do not self-medication.