Chronic hepatitis B needs treatment or not, depends on which phase of the hepatitis B disease process, hepatitis B disease process can be divided into four phases, not every infected with the hepatitis B virus need treatment, Chinese and Western medicine to regulate the immune therapy is not a reliable method, you can refer to the following comments, so as not to be deceived. 1. Immune tolerance period: mostly “triple positive”, that is, HBsAg (+), HBeAg (+), anti-HBc (+), HBVDNA (+), liver function is normal, mostly seen in adolescents and children infected. There is no need for treatment at this stage, remember! It is bragging or scamming to say that conversion is guaranteed. If you are older than 40 years old, it is recommended to do a liver biopsy, if the degree of inflammation and fibrosis is greater than or equal to grade 2 should be carried out Western antiviral therapy, the best choice of entecavir. 2. Immune clearance period: HBVDNA (+), liver function is not normal, certain patients HBeAg positive negative can be repeated. In this period, if the rise of ALT is more than two times of the upper limit of normal value, western antiviral therapy should be applied. Antiviral therapy with adjuvant drugs does not seem to be able to improve the efficacy of treatment, and it is recommended not to use them. If the increase of ALT is less than 2 times of the upper limit of normal value, it is better to observe or carry out general liver protection treatment, and if there is any change in the condition, go to regular hospitals to receive treatment in time. 3. Immune control period: in this period, HBsAg (+), anti-HBe (+), anti-HBc (+), i.e. “small triple positive”, normal liver function, HBVDNA (-). In this period, only regular review is needed, and no treatment is required. 4. Immune escape period: i.e. “small triple positive”, HBVDNA (+), abnormal liver function, patients in this period have the highest incidence of cirrhosis and hepatocellular carcinoma, and need to pay great attention to this period, especially patients with family history of hepatocellular carcinoma, and need long-term antiviral treatment. If the viral load is less than 5 times of 10 and liver function is normal or elevated less than 2 times of the upper limit of normal value, observation can be carried out and there is no urgency for antiviral treatment because some patients will clear the virus on their own, and the liver function will return to normal with the viral turnover. Entering the cirrhosis stage, western drug antiviral therapy is necessary, even if HBVDNA (-), western drug antiviral therapy is recommended. At present, only western drugs are effective in controlling viral replication in chronic hepatitis B. The efficacy of traditional Chinese medicine is not certain. If there are financial difficulties, western antiviral therapy alone is sufficient, and other traditional Chinese medicine and western drugs used in combination basically do not increase the efficacy of any treatment.