Uric acid is the end product of purine metabolism. The saturation and concentration of uric acid in the body at 37°C is about 420 μmol/L (7 mg/dl), and exceeding this concentration is considered hyperuricemia, and long-term hyperuricemia may lead to gout. There are two main types of causes of high uric acid: increased uric acid production and decreased uric acid excretion. The treatment of primary hyperuricemia and gout includes the following: 1. General treatment: control the total calories in the diet; limit the consumption of alcohol and high purine food; drink a lot of water to increase the excretion of uric acid; use drugs that inhibit uric acid excretion such as thiazide diuretics with caution; avoid triggering factors and actively treat Related diseases. 2.Treatment of hyperuricemia: The aim is to maintain the normal level of uric acid. Mainly include: uric acid-removing drugs such as benzbromarone, drugs that inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, and new uric acid-lowering drugs such as selective uric acid reabsorption inhibitors. 3. Treatment of acute gouty arthritis: After hyperuricemia develops into gout, colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. Management of interictal and chronic phases of gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; try to avoid or reduce the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control acute gouty arthritis attacks as soon as possible. Therefore, the treatment of high uric acid should be based on the cause and condition of the patient, and the combination of medication and general treatment is necessary to achieve better results.