The macula, a part of the retina, is a normal structure of the eye. Macula is mainly located in the optical central area of the optic nerve at the bottom of the eye, which is the projection point of our vision axis, it contains the most sensitive area of vision, if it has problems, it is called macular disease, which has a greater impact on vision. Due to the important position of macula, so it will have serious vision problems if it has slight problems, mainly or the following performance, such as seeing things distortion, central zone vision loss or dark spot, seeing objects appear color change, when the above situation occurs, then we should go to the specialist examination as soon as possible, we can do the following examination to clarify, such as fundus contact lens examination, OCT and other examination. Some of them are structural abnormalities such as macular hole macular pre-membrane, which can be treated by surgery to restore macular morphology and structure, while some of them are vascular in nature, which can be treated by using anti-VEGF drugs. Because each patient’s condition is different, such as whether there are other underlying diseases of the whole body, whether there is a history of drug allergy, whether there has been treatment, etc., the treatment plan is different for patients with different disease conditions. For macular degeneration, it is still necessary to make a specific and personalized treatment according to each patient’s specific situation, after a comprehensive examination and evaluation by a specialist, so as to have the best possible efficacy.