In recent years, due to advances in medical technology, the field of ophthalmology has become more and more knowledgeable about macular degeneration, and more and more tests and treatments are available. In ophthalmology clinical practice, more and more patients are being told that they have some kind of macular degeneration. Therefore the term macular is more frequently used by ophthalmic medical practitioners and patients. It is interesting to note that a significant number of patients tell others that he or she has macular growths in the fundus of the eye after an ophthalmic examination. Apparently these patients mistook the macula for macular degeneration. Therefore, in today’s increasing public health care awareness, we should strengthen the promotion of scientific knowledge so that the public can correctly understand the concept of macula and macular degeneration and better participate in self-care. The following is the difference between the two concepts: Macula: Macula is the anatomical name of the central part of the retina. Both morphologically and functionally the macula has special significance. Morphologically speaking, the macula is very small, generally identified as a 2mm area, with a depressed shape in its center and no blood vessels. The macula is rich in lutein, and the anatomical specimen is yellow, so it is called macula. Functionally speaking, macula is the most concentrated place of visual cone cell distribution, and how the macula functions determines the central vision (visual acuity). Therefore, macular lesions have a significant impact on vision. Macular lesion: macular lesion is the collective name of macular area lesion. Because there are more kinds of diseases in the macular area. When the diagnosis of the lesion is clear, the specific term of the disease is usually used, such as macular edema, age-related macular degeneration, mesoplasm, mesocoria, macular fissure, macular anterior membrane, etc. The term macular lesion is commonly used to summarize when the lesion is old or unclear in nature.