1, intraocular injection of drugs to treat which diseases: in age-related macular degeneration and some other macular diseases, due to a variety of reasons led to the growth of intraocular neovascularization, and the neovascularization is very brittle, easy to hemorrhage, oozing, edema, and ultimately lead to the formation of scarring, resulting in blindness. The anti-neovascularization drugs Ranibizumab (Lucentis; Nosodex), and Combsip (Conbercept; Langmu) are to stop the growth of neovascularization, reduce the leakage, and reduce the edema, so as to stabilize or improve the visual acuity. Currently, anti-angiogenic drugs have a wide range of applications: (1) macular edema caused by various reasons (including diabetic retinopathy, retinal vein occlusion, cataract surgery) (2) choroidal neovascularization caused by various reasons (including age-related macular degeneration, highly myopic macular degeneration, mesothelial seepage, etc.); Overall, vision can be improved by injections, but this is an average, and specific to the individual, there are actually There are those who don’t improve or even lose their vision. Depending on the condition, if it is already atrophic or scarred, the effect will not be good. For macular degeneration caused by mesophthalmos and pathologic myopia, most of them can be cured with 1-3 injections. However, for macular degeneration, diabetic retinopathy and macular edema caused by retinal vein occlusion, since it is a chronic disease, anti-VEGF drug treatment is to control the development of the disease and improve the visual acuity, which usually requires multiple treatments. 2.What are the side effects and complications of intraocular injection? A: At present, intraocular injection and photodynamic therapy are effective treatments for intraocular neovascular diseases. However, any treatment has its limitations. The greatest risk of intraocular injections is the complications associated with the injections, such as intraocular infections, hemorrhage, and retinal detachment. Fortunately, the incidence of serious complications is not high, but when they do occur, the consequences are more serious. The incidence of infection reported abroad is about 0.1%. 3.Preparation before injection and how to inject? To be injected 3 days before the antibiotic eye drops, if you can not use eye drops 3 days in advance, we must intensively point eye drops, such as a day point more than 10 times, only then can be injected. It is better to be accompanied by someone on the day of injection, and it is generally not recommended to inject both eyes at the same time. On the day of surgery, after registration, payment and signing the consent form, you will enter the operating room. In the operating room, the eyes will be sterilized, surface anesthetics will be administered, and the medication will be injected into the eyes at a distance of 3 or 5 mm from the corneal limbus. 4. What should I do after the surgery? A: You can open the gauze on the night of the operation, order antibiotic eye drops 3-4 times before going to bed, and do not wash your face that night. Starting from the first day after surgery, you can order eye drops for at least 3 consecutive days, at least 4 times a day. Normally you can return to normal life or work on the second day after surgery. However, if there is obvious eye pain, obvious blurred vision, eye redness and congestion, etc., you should contact your doctor immediately or consult the ophthalmology department of your local hospital, mainly to find out whether there is any infection occurring, and never delay!!!! 5.Photodynamic therapy (PDT) We have been carrying out photodynamic therapy for many years before the emergence of anti-VEGF drugs, and have rich experience in the treatment.PDT was the only treatment for intraocular neovascularization a few years ago, and it is really effective, which can make the neovascularization closed, and stabilize the vision. Another great benefit is that there are virtually no side effects or complications. Currently, we promote “combination therapy”, that is, PDT combined with intraocular injection to treat intraocular neovascular disease (especially polypoid choroidal vasculopathy), the purpose is to achieve better therapeutic efficacy at the same time, reduce the number of times of PDT or intraocular injections, reduce the cost, reduce the burden of the family to go back and forth to the hospital many times, and above all, reduce the side effects and the risk of intraocular injections. and risks of intraocular injections. One intraocular drug injection is performed, followed by PDT treatment, followed by a review in 4-6 weeks, and the next step in treatment as needed and appropriate. (1) Immediately after the operation, flocculent floaters in front of the eyes: it may be that the drug is floating in the vitreous, do not be nervous; (2) After the operation, go home and look in the mirror, the eyes have a lot of bleeding, and even purplish: it may be that the injection touches the bleeding of the small blood vessels, which is not scary, and is usually absorbed in 10 days or so. (3) On the day of surgery, your eyes hurt, your eyeballs can’t move, you have a lot of tears, and you have a sense of foreign body: it may be the effect of disinfectant, if the pain is really unbearable, you need to come to the hospital to see it; if it is still tolerable, it can be relieved on the next day in general. 7, I have been treated whether it can be fully recovered The macula is the most important part of our human eye vision, Division of our central vision, color vision, shape perception, so once the macula got sick, affecting the visual function is very serious. In some cases, because the time is too long, the nerve tissue has been irreversibly damaged, although the lesion site is not bleeding and edema, that is, we are medically cured, but leave a scar right in the center of the macula, so the vision will not be as good as not having had the disease, there may also be visual distortion!