The principles of treatment are divided into two aspects: one is symptomatic treatment of precocious puberty, and the other is etiological treatment of the causes of precocious puberty. In the treatment of abnormal puberty, it is important to get timely diagnosis and develop reasonable treatment plan. Different types of precocious puberty have different etiological factors, so treatment methods should be adopted for different etiological factors. In children with true precocious puberty, because of the involvement of gonadotropin-releasing hormone in the pathogenesis of the disease, the treatment method of injecting long-acting gonadotropin-releasing hormone analogues can be used for both men and women in order to block the release of pituitary gonadotropin and thus inhibit their premature puberty development. Later, the dose of the drug and the treatment regimen are adjusted according to the response to the drug. The choice of gonadotropin-releasing hormone analogues) treatment, although more expensive, can stop the rapid progression of bone age and prevent short stature. Although progesterone or megestrol treatment can also stop the development of secondary sexual characteristics in true precocious puberty and is inexpensive, it does not slow down skeletal maturation and therefore does not prevent short stature. At the same time, treatment should also be given for the primary causes such as intracranial tumors and infections, such as surgery, radiotherapy or chemotherapy for tumors depending on the situation. In children with pseudoprecocious puberty, treatment with injections of long-acting analogues of gonadotropin-releasing hormone is ineffective because the pathogenesis does not depend on the action of gonadotropin-releasing hormone. Instead, emphasis is placed on treatments that target various specific etiologies, such as removing the tumor that secretes sex hormones, cutting off the source of exogenous sex hormones, and using adrenal glucocorticoids to treat congenital adrenocortical hyperplasia. Or we can use drugs that directly inhibit the synthesis and secretion of sex hormones, etc. The purpose of treatment for children with precocious puberty is to return the child to a normal growth path similar to that of children of the same age and gender, and eventually to obtain a normal adult lifetime height, and to remove the primary causes of precocious puberty that threaten the child’s physical health. In order to ensure that the child can achieve the maximum adult lifetime height, many patients are now treated with recombinant human growth hormone produced by genetic engineering to promote growth. Studies on the clinical application of growth hormone have shown that the earlier the use, the younger the bone age, the better the results.