How to analyze liver function results?

  Analysis of liver function test results: 1. Causes of elevated ALT: (1) acute and chronic viral hepatitis (2) cholecystitis or biliary tract diseases (such as inflammation, stones, polyps, cancer, etc.); (3) liver damage caused by alcohol consumption; (4) liver damage caused by drugs; (5) other factors causing abnormal ALT (fatty liver, liver cancer, etc.); (6) viral hepatitis (hepatitis B, hepatitis C, hepatitis A, etc.) (6) viral hepatitis (hepatitis B, C, A, etc.).  (2) Analysis of glutamic transaminase results: Increased glutamic transaminase (AST) >60u/L; acute phase of myocardial infarction, acute hepatitis, drug-induced hepatocellular necrosis, active phase of chronic hepatitis, active phase of cirrhosis, hepatocellular carcinoma, myocarditis, nephritis, myositis.  3, ALT/AST ratio results analysis: AST is mainly distributed in the myocardium, followed by the liver, skeletal muscle and kidney and other tissues. Since about 80% of AST exists in mitochondria, it is less sensitive to hepatocyte damage than ALT and the magnitude of elevation is not as great as ALT, but if AST is substantially elevated it means that hepatocyte damage is more serious. Therefore, in clinical practice, the ratio of ALT/AST is often regarded as a diagnostic indicator and a condition monitoring indicator.  4. Analysis of γ glutamyl transpeptidase (GGT) results: GGT is mainly from the hepatobiliary system, therefore, it is mainly a monitoring item for hepatobiliary diseases.  (1) Liver inflammation: GGT is mildly and moderately increased.  (2) Other hepatobiliary diseases: hepatocellular carcinoma, hepatic obstructive yellow bile, biliary cirrhosis, cholangitis, gallbladder polyps, gallstones, pancreatitis, pancreatic head cancer, biliary tract cancer, etc., GGT is significantly elevated.  (3) Long-term or large amounts of alcohol consumption can also lead to elevation of this enzyme.  (4) Long-term acceptance of certain drugs such as phenobarbital, phenytoinamide, antipyrine, oral contraceptives, etc. will also increase GGT.  5. Analysis of bilirubin results: Bilirubin is the product of decomposition and destruction of aging red blood cells in the blood. It is divided into three kinds of bilirubin: total bilirubin, direct bilirubin and indirect bilirubin. Therefore, there are 3 aspects of bilirubin measurement results.  (1) When liver cells are damaged, such as in hepatitis, direct and indirect bilirubin will be significantly increased.  (2) Direct bilirubin in the blood is significantly increased by biliary tract diseases, especially gallbladder stones, biliary polyps, and cholecystitis.  (3) Hemolytic diseases increase the source of bilirubin in the blood, and the liver is unable to process it, resulting in a significant increase in indirect bilirubin.  6. Analysis of the results of total protein, albumin and globulin: The content of protein in the blood can reflect the function of the liver. If the protein decreases, it indicates that the synthetic function of the liver is damaged, which is a manifestation of a more serious condition, such as chronic active hepatitis, cirrhosis, liver failure, etc. Some non-liver diseases can also cause changes in blood proteins, so some physiological influences should be noted when analyzing the results.