1, psychological factors: a healthy psychological state helps the disease recovery, psychological disorders are mainly manifested as anxiety, fear and disappointment. This will affect the effectiveness of treatment, because bad emotions make the rehabilitation exercise enthusiasm is reduced, in addition to the negative psychological stress caused by a bad state of mind, acting on the organs and systems governed by the vegetative nervous system, through the endocrine system affects the whole body, but also detrimental to disease recovery. 2, diet and living: eat high protein, high nutrition food such as meat and fish, also eat fruits and vegetables to supplement vitamins, drink milk to supplement calcium, maintain a balanced intake of nutrients, avoid overweight to increase the burden on the joints, do not eat unclean food, do not drink raw water to prevent diarrhea. Alcohol should be prohibited while taking NSAIDs and methotrexate. Avoid too much satiety and tight clothing for those with late stage thoracic involvement. It is important to quit smoking because the disease often involves the spine and the thorax, resulting in reduced lung volume and easy shortness of breath, which can be aggravated by smoking. In addition, the disease does not increase the incidence of lung infections, but smoking can cause serious lung infections. Jiaxing First Hospital Rheumatology Department Zhang Bin 3, hygiene and environment: should keep warm and keep dry. Those who have long foreskin or prepuce should be circumcised, and pay attention to external genital hygiene, diligent flushing, pay attention to sexual hygiene, life check. 4, prevention of colds: in the epidemic season (spring and autumn) to avoid going to crowded public places, or close contact with people with colds; can be vaccinated, such as the annual influenza virus and pneumococcal inoculation, etc.; keep the home clean and hygienic, proper ventilation; keep a relaxed mood, avoid overexertion; enhance nutrition, improve immunity. 5. Fertility: The disease itself will not adversely affect the patient’s reproductive function, such as taking drugs that affect reproduction, such as Radix Rehmanniae or Kunming Shanghang, which can lead to amenorrhea or infertility; male patients taking salazosulfapyridine will have reversible sperm reduction, but once the drug is stopped, it can be restored. Pregnancy and childbirth should be carefully considered in advanced female patients who have developed joint or spinal deformities and are unable to care for themselves. If there are no severe spinal deformities, pregnancy is not a problem for women, but if there are severe hip deformities, a cesarean section may be required, and the position should be changed frequently while standing during pregnancy. Stop taking NSAIDs during the first 12 weeks and the last 4 weeks of pregnancy and during lactation. After 3 months of pregnancy, hydrotherapy in a warm pool is ideal. 6, posture and posture: (1) Sitting: choose a hard seat and a hard backrest high to the head with armrests, adjust the height of the chair, maintain the correct posture, avoid bending the body forward, chest upright, often move the spine, stretch the spine by sitting straight and moving the shoulders backward, avoid sitting on a low and soft chair or sofa. (2) standing: chest up, abdomen and eyes flat, do not stand or sit too long in one posture, often walk and stretch the body, or lie flat for 15-20 minutes (supine, legs hanging down), if you must maintain a posture, you should move and stretch the joints as much as possible. (3) sleep: supine position as far as possible to avoid flexion deformity, bed selection with ordinary bed (should be firm, not sagging, not too hard), mattress can have springs inside, but the side should be firm, can put cardboard or plywood between the mattress and bed board, choose when first lying on the mattress for 20 minutes to see if comfortable, pillow as low as possible to prevent cervical deformity, choose a fluffy feather pillow, poor sleep, can use amitriptyline. 7, adhere to exercise: as important as drug treatment. While controlling joint pain, joint activities should be performed in a timely, cautious and gradual manner. In the acute stage, let the affected joints move gently and passively to the extent that pain just appears, 1~2 times a day, and put the joints in functional position when not exercising. In the chronic phase, the pain duration after exercise <2 hours is the degree, at least one set of deep breathing activities every day to maintain thoracic mobility, more appropriate exercises are jogging, swimming and tai chi, etc. Swimming is the best exercise, swim in a variety of ways, to avoid high-intensity strenuous exercise, such as wrestling. When exercising, trainers with cushioning insoles should be worn. Those with hip joint lesions should insist on functional exercises to reduce disability. Routine physical therapy should be actively carried out, according to the daily precautions for patients with ankylosing spondylitis of the disease.