There are more reasons for waking up with headache in the morning, which may be due to lack of sleep the night before, excessive staying up late, drinking too much alcohol, and getting up too quickly may lead to postural hypotension, which occurs due to insufficient blood perfusion to the brain, thus leading to headache, timely adjustment of diet and regular rest and relaxation can generally correct the headache. There are also many diseases that can cause headaches, and the following are some of the more common causes: 1. Since normal blood pressure is volatile, blood pressure peaks in the morning, so patients may have headaches due to morning peak hypertension; 2. Intracranial tumors, cysts and other diseases can cause headaches, which require CT and MRI examinations of the head to help confirm the diagnosis; 3. When patients experience anxiety and depression, they are prone to Tension headache, which lasts for a long time, may wake up in the morning for several consecutive days with headache, accompanied by sleep disorders and difficulty in sleeping; 4. Diseases such as cold, frontal sinusitis, cervical spondylosis and migraine may also cause patients to wake up in the morning with headache. No matter what the cause of the headache is, if the symptoms are persistent or the pain is severe, or even accompanied by fainting, fever, vomiting and other discomforts, it is recommended to go to a specialist hospital for further examination and treatment after a clear diagnosis.