There is no clinical term for the best time to treat gallbladder stones, and the treatment time should be determined by the specific condition. Because medication usually cannot cure gallbladder stones, clinical treatment is based on surgical removal of the gallbladder, mostly laparoscopic cholecystectomy, which generally does not cause serious consequences as long as the stones are removed before they cause malignant lesions, and the timing of surgery for gallbladder stones generally varies in different cases. For children with gallbladder stones and asymptomatic gallbladder stones, they are usually not treated and only need to be reviewed regularly; for those with symptomatic gallbladder stones, and those with gallbladder stones combined with chronic cholecystitis, which is not in progress, cholecystectomy is not urgent, and most of them will not have serious consequences because the surgery is later or earlier, so there is no need to be nervous because the surgery is scheduled late or there are other reasons to delay the surgery. Elective surgery is usually recommended in cases of high number or excessive diameter of stones, thickened and calcified gallbladder wall, with gallbladder polyps, and in cases prone to symptoms and complications at a later stage. If the patient is in poor physical condition, such as anemia or dehydration, the patient needs to adjust the body indicators to basic normal before surgery. In patients with acute onset of gallbladder stones combined with cholecystitis, laparoscopic surgical resection can be performed as early as possible to avoid the continued development of inflammation-induced exudation and swelling affecting the surgical field, causing difficulties in microscopic surgery and even requiring conversion to open surgery. For patients with excessive inflammatory response, such as the presence of pain in the hepatobiliary area, jaundice, and fever, anti-inflammatory treatment can be administered first, and elective surgery can be performed after the inflammation subsides. Since gallbladder stones cause continuous irritation to the gallbladder wall, they can easily cause cholecystitis. Long-term inflammatory reaction of the gallbladder can lead to thickening of the gallbladder wall, loss of the function of storing and concentrating bile, and even gallbladder cancer may occur in severe cases. In addition, stones can easily get stuck in the pancreatic ducts during discharge along the bile ducts, which can easily cause acute pancreatitis with symptoms such as severe pain in the left abdomen, and if combined with infection, the condition is more critical. Therefore, if gallbladder stones are found, it is important to seek medical treatment as soon as possible. Generally, the removal of gallbladder does not affect the digestive function too much, and the impact is much smaller than if it is not removed, so it is more clinically advocated to remove gallbladder stones for patients with indications for surgery.