As the gold standard for the treatment of benign gallbladder diseases, laparoscopic cholecystectomy has been widely accepted, and rapid advances in laparoscopic techniques and instruments have pushed the surgical procedure in a more minimally invasive and cosmetic direction. Transumbilical Single Site Laparoscopic Surgery (TUSSLS or Transumbilical Single-port Laparoendoscopic Surgery, TUSSLS) has been developed clinically in recent years, especially for transumbilical single site laparoscopic cholecystectomy (TUSSLS). The first transumbilical single-port laparoscopic cholecystectomy was performed by Podolsky et al. in May 2007. TUSPLC is still in the early stage of development, and most of the operators screen the surgical subjects appropriately for reasons of surgical safety and success rate, so its selection of surgical subjects is more strict compared with classical multiport laparoscopy: 1. The average age of the largest reported case is 39 years old (29-63 years old), the maximum age of the patients is 67 years old and the minimum age is 23 years old, and the age of the first reported TUSPLC patient in China is 25 years old; 2. Number of acute attacks <1. The following patients are temporarily excluded from the surgery: 1) severely obese; 2) patients with cirrhosis; 3) history of peritonitis; 4) history of upper abdominal surgery; 5) history of recent attacks of cholecystitis; 6) other gallbladder pathologies such as gallbladder abscess; 7) people at high risk for general anesthesia. At present, the surgical instruments of TUSPLC are still in the process of continuous exploration, experimentation and innovation. The advantages of TUSPLC: First, it is more minimally invasive and cosmetic. TUSPLC reduces the number of incisions and the interference of the surgery with the abdominal cavity, and patients recover faster. It also makes good use of the physiological characteristics of the umbilicus depressed on the body surface, effectively hiding the surgical scar and eliminating the need to make secondary incisions in other parts of the abdominal wall to achieve a visual scar-free effect, which has good cosmetic value. Second, flexibility. When the intra-abdominal tissue adhesions, gallbladder atrophy, abnormal anatomical position of the gallbladder and other reasons make the surgery difficult, the operator can choose to add an auxiliary trocar under the right midclavicular line rib margin or under the glabella to turn into a multi-hole laparoscopic surgery to achieve successful minimally invasive surgery. This also ensures that the procedure is as safe as possible under the principle of minimally invasive surgery. Recently, I have gradually performed more than 20 cases of TUSPLC surgery, and I have learned that the guidelines for such surgery must be strict, and the operating skills for multiport laparoscopic surgery must be quite proficient and familiar with extrahepatic biliary tract anatomy and common anatomical variants. If necessary, we should transit to three-hole or multi-hole laparoscopic surgery, or even open surgery.