Most syphilis can be cured, except for stage III syphilis, or late syphilis, which has caused irreversible damage to many organs in the body and is difficult to allow recovery. The treatment time for syphilis is generally long, starting from receiving treatment, and usually requires observation for 2-3 years. After regular treatment in the first year, serological review is required every 3 months to observe the treatment of the disease. If the disease is well controlled, it will be reviewed every 6 months in the 2nd-3rd years. If the test results are normal for 3-4 times in a row during the review process, the disease can be judged as cured at this time.