Some time ago, an elderly man was seen who had been drinking alcohol all his life, basically 3-4 taels a day. Recently, due to abnormal liver function and blood sugar levels, he was persuaded by his family to make up his mind to give up alcohol. As a result, on the third day of quitting alcohol, he suddenly developed symptoms such as irritability, slurred speech, and profuse sweating. Combining the medical history and examination results, the patient was initially judged to be suffering from alcohol withdrawal syndrome, and after giving appropriate treatment, the patient has now been discharged from the hospital. During the communication with the family, the family asked confusedly, “I only know that drinking is bad for the body, how can quitting alcohol also damage the body? For patients who have been drinking alcohol for a long time, their central nervous system (brain and spinal cord) is in a state of functional inhibition under the effect of alcohol for a long time. If they suddenly stop drinking, the inhibition of the brain by alcohol will suddenly disappear, resulting in cortical (or) β-adrenergic hyperexcitation, and triggering symptoms of cortical hyperexcitation such as restlessness, confused language, epilepsy, etc., which can be serious and lead to life-threatening conditions. Prevention of withdrawal syndrome is important. When a patient is determined to prepare to quit drinking or cannot drink for other reasons, family members should, under the guidance of a doctor, advise the patient to gradually reduce the amount of alcohol consumed over a period of 5 to 7 days, and then to quit completely and take a small dose of Valium to prevent the appearance of mild withdrawal symptoms. When headache occurs, besides applying analgesic drugs, because long-term drinkers often suffer from nutritional deficiencies due to alcoholic beverages not containing vitamins, minerals, amino acids and other nutritional components, it is also necessary to supplement potassium ions, magnesium ions, vitamin B, etc. to improve the function of blood vessels and nerves, which is beneficial to the treatment of headache. Patients should be closely observed for withdrawal syndrome after quitting alcohol, and those with more severe symptoms should be promptly hospitalized.