The main component of liquor is ethanol, and regular drinking, whether in the morning, noon or evening, can be harmful to the body and cause various diseases, which is detrimental to health. 1. alcohol dependence: long-term drinking can produce alcohol dependence, that is, the formation of alcohol addiction, which has adverse effects on the body. And after drinking alcohol may inhibit brain activity, leading to alcohol poisoning and other situations; 2, affect sleep: drinking alcohol does not help sleep, but will increase neural excitability, affecting the quality of sleep. Drinking alcohol at night may lead to sleep breathing disorder, raise blood pressure, cause coronary artery spasm, angina pectoris, myocardial infarction, etc.; 3, cause gastrointestinal disorders: regular alcohol consumption is likely to lead to gastrointestinal damage, weakening the absorption function of the gastrointestinal tract. For people with basic gastric disease, alcohol stimulation can cause gastric disease, leading to gastric ulcers, which can lead to gastric cancer in serious cases; 4, increase the burden on the liver: ethanol is mainly metabolized through the liver, long-term drinking will increase the burden on the liver, causing alcoholic liver disease, and even cause alcoholic cirrhosis, which can lead to liver cancer in serious cases; 5, damage to the brain: regular drinking can damage the brain, intellectual decline. And susceptible to alcoholic encephalopathy, manifested as limb sensory numbness, activity disorders, ataxia, etc.. Drinking during special periods is even more detrimental to health, such as drinking during pregnancy can lead to fetal alcohol syndrome, resulting in fetal physical, intellectual and behavioral problems; long-term drinking during adolescence can lead to stunted growth and reduced brain capacity; and old age can increase the chances of Alzheimer’s disease. In addition, long-term alcohol consumption can increase the risk of oral cancer, throat cancer, esophageal cancer and breast cancer. It is recommended to have a nutritious diet and avoid bad living and eating habits.