Sequelae from organophosphorus poisoning have a low chance of recovery, which can only be facilitated by immediate neurotrophic treatment in the early stages of the disease, but is not completely curable. Mild or moderate organophosphorus poisoning usually does not lead to obvious sequelae. Only severe organophosphorus poisoning can lead to the occurrence of sequelae, common sequelae are cerebral tissue ischemia and anoxic injury or delayed encephalopathy, etc., are serious brain tissue damage, so the chances of complete recovery are very small. After the brain tissue damage caused by severe organophosphorus pesticide poisoning, neuroprotective drugs, such as methylcobalamin or vitamin B, should be taken as soon as possible under the guidance of doctors. The correct use of neuroprotective drugs can effectively promote the recovery of brain nerves, thereby alleviating the discomfort brought about by brain nerve injury. At the same time, with appropriate hot compresses and physiotherapy, etc. can also effectively relieve the symptoms of local muscle stiffness or facial nerve damage. In the event of organophosphorus poisoning, it is recommended to go to the hospital immediately for first aid treatment, which can be done through gastric lavage or vomiting to remove the drugs, and it is recommended to choose the appropriate drugs for the treatment of the after-effects under the guidance of the doctor.