Whether a hematopoietic stem cell transplant at the age of 65 will be successful or not is not absolute, and it has to be judged in detail according to a variety of factors such as the method of transplantation, the severity of the disease, and one’s own physical condition, etc., and the specific situation varies from person to person.
Generally speaking, hematopoietic stem cell transplantation can be used for the treatment of aplastic anemia, hematologic malignancies, such as leukemia, lymphoma, etc., and can be divided into two different ways: autologous and allogeneic stem cell transplantation.
Compared with allogeneic stem cells, autologous stem cell transplantation has less rejection reaction after surgery. However, autologous stem cell transplantation is generally only used for the first transplantation of lymphoma and multiple myeloma. In contrast, acute leukemia (non-M3) and acute aplastic anemia require allogeneic stem cell transplantation.
In addition, if the patient’s condition is not particularly serious and he or she is in good health, the success rate of stem cell transplantation will be higher and complications are less likely to arise after the surgery. However, if the condition is serious or the physical condition is poor, then the success rate will drop drastically, and even if the surgery is successfully completed, there is still a possibility of relapse after the surgery.
However, not all 65-year-old patients are suitable for HSCT. It is recommended that they undergo an examination before undergoing the procedure, and the doctor will formulate a suitable surgical plan to prevent their condition from deteriorating, which could be life-threatening.