1, the gallbladder is an important organ of the human body, with the role of storing concentrated and excreted bile and regulating the pressure of the bile duct, and recent studies suggest that the gallbladder is also an important immune organ of the human body, not dispensable. From the viewpoint of modern medicine, all organs that can be preserved should not be removed, and the real minimally invasive is to preserve the function of the organ to the maximum extent. 2, endoscopic minimally invasive biliary surgery is minimally invasive, high-tech, new technology, which is different from the previous lithotripsy choledochoscope, which is based on fiber endoscopy in order to complete minimally invasive observation, removal of stones and polyps, so as to scientifically decide whether to preserve or cut bile. 3, due to the widespread use of B-type ultrasound examination in clinical practice, a large number of gallbladder polyps have been found, reflecting the true incidence of gallbladder polyps, but it cannot accurately identify the nature of the masses, however, the endoscopic minimally invasive biliary polyps removal method can easily solve this problem, which is another great progress of endoscopic surgery. Endoscopic choledocholithotomy and traditional cholecystostomy have essential differences, endoscopic choledocholithotomy is under the direct vision of fiber choledochoscope, using the basket to remove all the stones, and the fiber choledochoscope has no dead angle of vision, the mirror can reach the cystic duct; while cholecystostomy is under the non-direct vision with surgical instruments to clip the stones, with great blindness, easy to clip the stones, resulting in stone leakage. 5. There are a series of side effects after cholecystectomy, including the following: (1) indigestion, abdominal distension and diarrhea. (2) Gastric reflux of duodenal fluid after cholecystectomy, resulting in bile reflux gastritis or esophagitis. (3) Increased incidence of common bile duct stones after cholecystectomy. (4) The problem of bile duct injury resulting from cholecystectomy. (5) The effect of cholecystectomy on the incidence of colorectal cancer. (6) Post-cholecystectomy syndrome. (6) Low recurrence rate after minimally invasive cholecystectomy. The recurrence rate of minimally invasive biliary surgery is only 0.1% for gallbladder polyps and 3.9% for gallbladder stones after 1-14 years of follow-up, which is a safe and reliable surgery. It has a broad development prospect. In summary, there is an essential difference between biliary preservation and cholecystectomy. With the development of modern medical science and technology, there is a better understanding of the gallbladder as an important digestive organ, which is a complex chemical and service free organ in addition to its role in concentrating, contracting and regulating the pressure of the buffered bile duct. It is not a dispensable gallbladder, but a very important digestive organ, so it should not be easily abolished. Of course, in cases of gallbladder atrophy, gallbladder is no longer functional, or gallbladder polyps are suspected to be cancerous, the gallbladder should undoubtedly be removed to remove the lesion.