The treatment of scleroderma includes the use of drugs such as glucocorticoids, immunosuppressants, vasodilators and general therapy. 1. Glucocorticosteroids: such as prednisone and methylprednisolone are the most commonly used therapeutic drugs, which can reduce the symptoms of skin edema in the early and acute stages, and also improve lung inflammation. However, there is a risk of elevating blood sugar and causing blood pressure to rise, so pay attention to monitoring the side effects during the use of medication. 2. Immunosuppressant: It is applicable to the situation when internal organs begin to be involved, and has the effect of stopping the long-term progress of scleroderma. Commonly used drugs include methotrexate and cyclosporine. 3. Vasodilators: vasodilators such as nifedipine tablets and prostaglandin sodium have the effect of improving circulation and Raynaud’s phenomenon. 4. General treatment: patients need to quit smoking and keep hands and feet warm. Patients with gastroesophageal reflux should eat small meals and take a standing or semi-recumbent position after meals to prevent ulcers such as gastroesophageal reflux. It is recommended that patients diagnosed with scleroderma go to the rheumatology and immunology department of regular hospitals as soon as possible, and use medications under the guidance of professional doctors.