Soy isoflavones can be used to improve premature ovarian failure, which often manifests itself as estrogen deficiency symptoms such as reduced menstrual flow and early menopause, and soy isoflavones are a non-steroidal functional active substance extracted from soybeans with estrogen-like activity, which has certain ovarian premature failure prevention and body health effects. However, the effect is usually limited and it is recommended to use other hormonal drugs or Chinese medicine for treatment under the guidance of a doctor. Soy isoflavones have a chemical structure similar to that of the endogenous hormone estradiol and have an estrogenic effect when ingested into the body, which is effective in relieving premature ovarian failure. The patient can take soy isoflavones to reduce the burden of ovarian hormone secretion and delay the decline of ovarian function, which can achieve certain treatment or prevention of premature ovarian failure. Especially for women who are approaching menopause, the level of estrogen in the body drops sharply, which not only leads to abnormal ovarian function, but also leads to diseases such as osteoporosis. Soy isoflavones also have an antioxidant effect, reducing oxidative stress damage to cells, and can improve bone formation and delay the progress of osteoporosis to achieve health effects. However, it is not recommended to use the medication without doctor’s guidance. It is recommended that the doctor conduct a comprehensive assessment and guide the medication. If there is a contraindication to the use of medication and after self-medication, it may cause more serious results. If a patient has premature ovarian failure, the cause should also be identified, with or without obvious secondary factors, and actively managed. If remission cannot be obtained with the application of soy isoflavones, other medications should also be used as prescribed by the doctor.