The cause of ichthyosis is mostly related to genetic factors, or may also be caused by systemic diseases, medications, etc. Its symptoms are often characterized by dry, rough, thickened skin with ichthyotic scales, etc. The symptoms of ichthyosis are characterized by dry, rough, thickened skin with ichthyotic scales. Ichthyosis is a group of keratosis disorders characterized by dry skin with ichthyosis-like scales. The cause of ichthyosis is mostly related to genetic factors, such as the inheritance of mutated or missing genes from parents, which affect the body’s ability to protect the skin and keep it moist, as well as the rate of proliferation or shedding of skin cells, resulting in ichthyotic scaling of the skin. Ichthyosis may also be caused by systemic diseases such as tuberculosis, thyroid disease, lymphoma, dry syndrome, etc. Acquired ichthyosis can also be secondary to reactions to a variety of medications, such as niacin and triamcinolone acetonide. Ichthyosis clinical often manifested as limb extensor or trunk skin dry, rough, with rhombic or polygonal scales, appearance such as fish scales or snakeskin, skin cracks, epidermal rigidity, resulting in their own sweat hair scarcity, sweating abnormalities, resulting in the body of water metabolism imbalance, affecting the endocrine system. Patients can use Calcipotriol betamethasone ointment, isotretinoin soft capsule and other drugs for treatment, during the treatment, pay attention to a light diet, avoid spicy and stimulating food, usually also need to pay attention to personal hygiene, rest, avoid staying up all night and overwork. Therefore, if the above symptoms occur, should pay attention to, timely medical treatment, so as not to delay the condition. The above drugs must be used under the guidance of a doctor.