Ichthyosis may be inherited across generations. Ichthyosis is mostly caused by heredity, it may be that the patients inherited the mutated or missing gene from their parents, some people carry the gene of ichthyosis in their body but have no clinical symptoms, this situation may pass on the mutated gene to the next generation to show symptoms when giving birth, and the phenomenon of intergenerational inheritance occurs. Although ichthyosis has a genetic tendency, but it is not 100% will develop, and intergenerational inheritance is not regular, this disease although incurable, but will not affect the patient’s life expectancy, under the guidance of the doctor regular treatment can improve the patient’s quality of life. Hereditary ichthyosis usually develops in early childhood or as a newborn with symptoms such as dry skin, mild or moderate flaking, and scales like fish scales. If ichthyosis is suspected, it is important to seek medical attention for a detailed examination and early treatment.