Babies suffering from neonatal hemolysis will have various symptoms, mainly manifested as the following: first, jaundice. Red blood cell destruction decomposes bilirubin in a yellow color, which can be distributed throughout the body, causing the body tissue to turn yellow. Because the skin and sclera are located on the surface of the body, the yellowing is most obvious, that is, jaundice. Most newborns show signs of jaundice after birth, but when jaundice appears too early, develops too quickly or the bilirubin level in the blood is too high, it is important to watch out for the development of hemolysis. Jaundice in infants with hemolysis often appears within 24 hours after birth or on the second day. Second, a common symptom is anemia. Due to the destruction of red blood cells, children with hemolysis will have mild to severe anemia. Third, hepatosplenomegaly. In severe anemia there is fetal edema with marked hepatosplenomegaly. Fourth, bilirubin encephalopathy. When the bilirubin level in the blood is too high, it can damage the brain cells and cause bilirubin encephalopathy. This is the most serious comorbidity of hemolysis, which usually occurs 2-7 days after delivery and manifests as increased jaundice. The child develops neurological symptoms, such as lethargy, feeding difficulties, double vision, and convulsions. Fifth, fever. Fever may be a reaction of the body after pediatric hemolysis, or it may be a history of more severe bilirubin encephalopathy; the fever may not be high, but if it occurs due to the latter, it indicates a more serious condition.