Bromadiolone is a bicoumarin anticoagulant rodenticide, which is one of the more common types of clinical rodenticide poisoning, and once it occurs, it needs to be seen in the emergency department of a hospital. Resuscitation of bromadiolone poisoning can be divided into the following aspects: 1. Stop contact: Stop contact with the poison and remove it. Patients with oral poisoning should be induced to vomit by pressing the tongue root, followed by gastric lavage, or take mannitol to induce diarrhea or enema to promote the discharge of toxic substances in the gastrointestinal tract; patients with skin infection should wash the skin thoroughly with water; 2. Application of antidote: apply the antidote vitamin K1. For those who do not have bleeding tendency and whose prothrombin time and prothrombin activity are normal in laboratory examination, they can temporarily not use Vitamin K1 treatment, but need to closely observe the status. If bleeding symptoms appear, then vitamin K1 treatment is required. It is usually used for 10-14 days until the bleeding disappears and the prothrombin time and prothrombin activity are normal and then the drug is discontinued. However, these rodenticides have a long accumulation time in the body and often have recurrent bleeding symptoms, requiring repeated treatment for up to 2-6 months. In addition, adrenocorticotropic hormone can be applied to reduce capillary permeability, protect platelets and coagulation factors, and promote hemostasis, while high doses of vitamin C can be considered; 3, plasma input: for those with severe bleeding symptoms, fresh plasma, fresh blood, prothrombinogen complex and other blood products can be input to help stop bleeding quickly; 4, symptomatic treatment: according to the appearance of other symptoms symptomatic treatment, such as psychiatric symptoms If you have psychiatric symptoms, give diazepam intravenously, moderate sedation; if excessive fluid loss occurs due to gastric lavage and catheterization, you can intravenously enter converted sugar electrolyte injection. Anticoagulant rodenticide has slow action and long incubation period after poisoning, most of them are 2-3 days or even 1 week before the symptoms of poisoning appear, generally the first to appear is hematuria, nasal bleeding, gum bleeding, subcutaneous bleeding, serious cases may appear vomiting blood, blood in the stool, bleeding of other important organs, shock may occur, patients often die of brain hemorrhage or myocardial hemorrhage. Therefore, once you suspect exposure to large amounts of bromadiolone, or have unexplained bleeding, seek medical examination in a timely manner.