Food poisoning should seek medical treatment in time, according to the situation by professional doctors for general treatment, rehydration, control of vomiting and diarrhea, antispasmodic and analgesic, gastric lavage or enema, anti-infection, anti-shock, hemofiltration and so on. 1. General treatment: first of all, bed rest is recommended; those with relatively mild symptoms can have a liquid diet; those with severe vomiting should fast. 2. Rehydration: vomiting and diarrhea will lose a lot of body fluids, which should be replenished in time. In mild cases, oral rehydration is the mainstay, and intravenous rehydration can also be given to avoid electrolyte disorders caused by dehydration. 3. Control vomiting and stop diarrhea: metoclopramide can be given to relieve vomiting symptoms, and pantoprazole can be given to inhibit gastric acid secretion. Diarrhea is obvious can be given montelukast and other astringent relief. 4. Antispasmodic pain relief: abdominal pain is obvious, consider the intestinal spasm caused, give scopolamine and other drugs to relieve. 5. Gastric lavage or enema: mainly for special types of poisoning, such as botulinum toxin bacillus poisoning, can be given sodium bicarbonate and other alkaline liquid gastric lavage or enema, reduce the toxicity of botulinum toxin bacillus. 6.. Anti-infection: choose antibiotics for different pathogenic bacteria, e.g. penicillin can be used for Staphylococcus aureus, cephalosporin or levofloxacin for gram-negative bacilli. 7. Anti-shock: severe food poisoning can lead to toxic shock, rapid rehydration should be carried out, and vasoactive drugs such as norepinephrine and dopamine should be used if necessary. 8. Hemofiltration: Severe food poisoning may lead to shock and systemic inflammation, multiple organ insufficiency, etc. Hemofiltration can be performed early to remove toxins and inflammatory mediators. Once poisoned, one should seek medical treatment as soon as possible, do not dispose of it on one’s own, thus delaying the time of treatment.