Sleeping toe pain may be a manifestation of gout. Most patients with this disease have elevated blood uric acid, which is caused by high blood uric acid resulting in the production of gout stones in the patient’s toes, and the pain in the toes usually occurs at night while sleeping and is more difficult to bear. If the patient is usually obese, it is also likely to occur. When you have gout, you should tell your patients to control their diet, eat less fatty meat and offal, quit smoking and drinking, and to exercise properly, control their weight, and eat less seafood.