Liver disease progresses from chronic hepatitis to cirrhosis, with different types and severity of manifestations, and its symptoms vary from none to very severe, for example, the following: fatigue, general weakness; nausea, vomiting, loss of appetite; weight loss; weight loss due to loss of appetite and disease consumption, muscle and fat loss, but also weight gain due to swelling and ascites formation. 1, abdominal distension In chronic liver disease, there may be vague pain in the upper abdomen or a feeling of distension in the upper abdomen due to indigestion and intestinal flatulence. 2. Jaundice In liver or biliary tract diseases, one of the metabolites in the body, bilirubin, is not excreted properly and is deposited in the sclera or skin, resulting in a yellowish stain. Scleral jaundice appears earlier. Even if the skin is yellowish, jaundice cannot be considered to have occurred if the sclera is not yellowish. The bilirubin accumulated in the body is partially excreted in the urine, so the urine becomes darker, and some patients think it is “red urine”. 4. Tendency to bleed In liver disease, gum bleeding or nose bleeding often occurs because the liver cells cannot adequately synthesize clotting factors. 5.Abdominal swelling and puffiness In cirrhosis, there is swelling in the frog’s abdomen or the whole body due to the production of ascites. 6.Vomiting blood, blood in stool or black stool Patients with cirrhosis may have bleeding in the esophagus or stomach. In cirrhosis, blood flow through the liver is difficult and returns to the heart through side branches. The most important of these are the esophageal veins and the gastric veins. Normally these veins are invisible, but during cirrhosis the blood flow through them increases, the pressure inside the veins rises and the veins thicken, called “varices”, which can be life-threatening if they rupture. Patients with cirrhosis who vomit blood should be taken to the hospital emergency room immediately. When the esophagus, stomach, small intestine and other parts of the bleeding, often appear vomiting blood or black stool. 7.Decreased libido or sexual dysfunction In chronic liver disease, sexual dysfunction such as testicular atrophy, erectile insufficiency and menopause may occur due to the imbalance of sex hormone levels, and males may experience breast enlargement.