One of the main symptoms of end-stage patients is dyspnea, so it is crucial to ask patients if they are having difficulty breathing. The main treatment for dyspnea is opioid medication and oxygen, and an oxygen bag or cylinder can be kept at home. Another major symptom of end-stage cancer patients is mental disturbance. In the last days of life, most patients experience irreversible delirium, which is associated with drug side effects, pain, and bladder urinary retention. There are also changes such as decreased eating, increased bed rest or sleep time, and the patient becomes less likely to be awake or awake for only a short time during the day, when the patient may experience “death grunts” during sleep. During the final period of death activity, the patient enters a comatose state with altered breathing patterns, a dramatic drop in heart rate, and petechiae on the extremities. Some patients also experience a “return to light” a few days before death, with a sudden increase in appetite and mental improvement, which can lead family members to believe that the disease has taken a turn for the worse.