How long a patient can live with hepatitis B is affected by many factors. Active and effective treatment may not affect the life expectancy, while untreated patients may develop cirrhosis and liver cancer in 10-30 years, thus affecting the life expectancy. The hepatitis B surface antigen, hepatitis B e antigen and hepatitis B core antibody are positive in the hepatitis B penta test of the patients with triple III positive, and it is necessary to combine them with the liver function to determine the survival time of the patients. Triple positive patients may be hepatitis B carriers, only regular testing of liver function and hepatitis B five can be; if triple positive patients and liver function abnormalities, by active antiviral treatment, may not affect the life expectancy, but if the treatment is not, the condition can gradually develop, most of the 10 years or so can develop into cirrhosis; if the cirrhosis to the advanced stage of cirrhosis, the patient’s survival period is about 5-10 years. Triple III suggests that viral replication in the body is more active, but it does not indicate its severity, as long as the patient actively cooperates with the treatment, most of them can effectively prolong the survival time. It is especially important for patients with triple III to undergo regular checkups and to determine whether treatment is needed based on the tests.