1.Does the weather affect the condition? Weather affects people’s mood, and mood is related to many skin diseases; ichthyosis is especially affected by weather, usually in cold seasons such as early spring, late autumn and winter, due to vasoconstriction, sebum and sweat gland secretion is reduced, the skin does not get too much moisturizing, and the rash will be aggravated. The heavier ichthyosis also feels uncomfortable in the hot summer due to poor sweating function, with itching and other discomfort. As the skin barrier function is affected, sweating can cause itching and scratching can lead to eczema, etc. Depressed mood in bad weather can also aggravate ichthyosis. 2.How should I deal with itchy skin and will scratching aggravate the disease? Some patients are prone to itching due to dry skin or eczema dermatitis at the same time, so they should actively moisturize their skin, rinse with water, apply suitable moisturizers such as urea cream, soothing vitamin E moisturizer (Nareya), etc., and take oral anti-allergy and anti-itch drugs such as loratadine, compound glycyrrhetinic acid tablets (Mennen), etc.; painful skin is mainly caused by cracks or scratching, so generally apply urea ointment or anti-infection drugs such as Bactrim. Anti-infection drugs such as Bactrim can be applied. As the skin barrier function of ichthyosis is damaged and the skin becomes brittle, avoid scratching as much as possible, on the contrary, scratching will aggravate the condition, easily induce eczema dermatitis or skin infection, aggravate the itchy and sensitive stimulation of the skin, and easily form a vicious cycle of itching – scratching. 3, how to choose and use skin moisturizer? How many times a day, only for the affected area or the whole body? There are many kinds of skin moisturizers and different types, generally according to the characteristics of their own skin, the severity of the lesions or the affected areas, etc.. For example, in summer and autumn when the temperature is high, use refreshing emollient moisturizers such as soothing moisturizing cream (domestic brands such as Neroliya, Winona, Yuze, etc.) and urea cream, etc.; if it is dry or winter, use oil agents such as medical petroleum jelly, or olive oil or urea lipid or soothing moisturizing oil, etc. Generally wash or bath after the skin is loose when the application effect is good, during the day to apply more times according to their dryness, under normal circumstances three times a day is better. Generally recommended for the affected area or particularly dry places, oil is not recommended for the whole body, is not conducive to the breathing of the skin, especially the neck, armpits, the inner side of the femur sweating more places is not recommended to apply. 4.Will doing some activities with large amplitude and pulling the skin aggravate the disease? As the dry and cracked skin of ichthyosis is more obvious, it is generally not recommended to do sports with larger pulling, which will affect the cracking of hands and feet, while excessive sports triggering a lot of sweating will aggravate ichthyosis, or the patient will feel very uncomfortable due to excessive sports, but the sweating function will be affected, even triggering heat stroke, etc. Proper exercise will accelerate the blood microcirculation of the skin and help improve the dry skin. Especially the couple or couples touch and sex much improve ichthyosis effect is obvious. 5.How many days should patients take a bath, and is there any special requirement for shampoo and bathing solution? For ichthyosis suitable water temperature bath or shower is helpful, short time bath or shower every day is fine, but it is not recommended to have stimulating soap or body wash, etc. It is fine to use mild and non-stimulating body wash appropriately, and it is better to use more water. Suitable shampoo is necessary, but it is not recommended to use anti-dandruff shampoo, rinse clean again and again after washing, and use skin care elements, etc. appropriately. 6.Does smoking and alcohol have any effect on the disease? Is there any taboo diet? Generally a small amount of alcohol, especially red wine, is helpful to improve microcirculation and can reduce the occurrence of ichthyosis, but some patients are often combined with eczema and other allergic skin diseases, it is not recommended to drink alcohol; smoking is not only easy to trigger or aggravate allergies, but also will affect the blood microcirculation of the extremities for a long time and aggravate the dryness of the skin, etc. However, if you have eczema and other allergic diseases, you should avoid spicy and irritating food, such as wine, garlic, onion, leek, chili, etc.; animal protein, such as fish, shrimp, mutton, chicken, beef, etc.; other things such as parsley, eggplant, parsley, celery, mushroom, etc. As far as possible, you should pay attention to which diet will affect your allergy and avoid it. Patients with ichthyosis are advised to take vitamin A and E rich foods, such as cod liver oil, carrots, cream, white potatoes, green leafy vegetables and pig liver. 7.Does sunlight have any effect on the disease? Ichthyosis generally has no special requirements for sun exposure, and the disease will not be aggravated by sun exposure. However, since the skin of ichthyosis patients has poor water fixation and moisturizing function, they can easily lose water, so they must pay attention to moisturizing and drinking more water when sunbathing, and the time of sunbathing should be shorter than normal people, otherwise the skin is more prone to dryness and pain than normal people, and easily get sunburned.