Premature ovarian failure (POF) is a condition in which women who have established regular menstruation develop persistent amenorrhea and sexual organ atrophy before the age of 40 due to a decline in ovarian function, often with a rise in gonadotropin levels and a decline in estrogen. Most patients experience pre- and post-menopausal symptoms such as sparse menstruation, amenorrhea, hot flashes, excessive sweating, heartburn, insomnia, vaginal dryness, and decreased libido. It is also accompanied by loose and rough skin, sagging uterus, non-ovulation, and hair loss. According to statistics, the incidence of POF in the general population is about 1% to 3%, and the incidence is about 0.1% before the age of 30 and 0.01% before the age of 20. In the last decade, the figure has increased year by year, and the age of onset tends to be younger. Therefore, the prevention of premature ovarian failure in young women is a matter of urgency. Let us look at the possible factors affecting premature ovarian failure: 1. The most important thing is that you have to be able to get a good idea of what you are doing. Some women, especially urban white-collar workers, are in a fast-paced, high-stress environment for a long time, and the central nervous system and hypothalamus-pituitary-ovarian axis dysfunction, resulting in follicle stimulating hormone, luteinizing hormone abnormal secretion, ovulation dysfunction, amenorrhea, which leads to ovarian hypofunction and reduced hormone levels. Coping strategy: get rid of stress and anxiety at the right time, de-stress yourself, release bad emotions and keep your mood relaxed. 2. Gonadal infections. Pelvic infections may be an important cause of premature ovarian failure. Infectious factors associated with POF include viral infections, bacterial infections, and atopic infections. The invasion of viruses, bacteria, and Mycobacterium tuberculosis into the ovaries leads to post-inflammatory fibrosis of the ovaries and a decrease in the number of follicles, which can develop into premature ovarian failure. It has been confirmed that women who have suffered from viral mumps at an early age are more prone to premature ovarian failure, which is strongly related to viral invasion of ovarian cells and tissues, resulting in decreased ovarian function and atrophy of reproductive organs. Coping strategies: Pay attention to vaccination and reproductive health from early childhood. Insist on exercise to strengthen the immunity of the body. Prevention and treatment of septic, tuberculosis and gonorrheal pelvic inflammatory disease is also very important. 3, drug influence. These include emergency contraceptives, antineoplastic drugs, antidepressants, drugs for insomnia and tretinoin, etc. These drugs can inhibit ovarian function for a long time, leading to dysfunction, abnormal secretion of sex hormones and ovulation, and eventually ovarian function decline. Response strategy: do not easily (long-term) take emergency contraceptives, take the drug before reading the adverse effects of drugs, or under the guidance of a doctor regular use of drugs. 4, excessive weight loss. Most women in the pursuit of “white and thin beauty”, they will lose weight by dieting, eating vegetarian and other unhealthy ways. If blind dieting and long-term vegetarianism can lead to malnutrition and affect the function of the pituitary gland, leading to insufficient gonadotropin secretion and atrophy of the ovaries with reduced function. Response strategy: balanced diet, balanced nutrition, choose a scientific and healthy way to lose weight. Eat more fresh vegetables and fruits can resist premature ovarian failure. 5. Over-stimulation of the ovaries. In recent years, due to the delay in the childbearing age, some women are forced to use the option of ovulation to increase the chances of pregnancy, but if the ovaries are over-stimulated, the ovaries are still very damaging and can easily cause the decline of ovarian function. Coping strategies: Getting rid of the pressure and having children at the right age is the way to go. Infertility, it is recommended to go to a regular specialist hospital for treatment. 6. Genetic and autoimmunological diseases. Premature ovarian failure may be related to the genetic factors of chromosomal abnormalities in patients. Premature ovarian function decline may also be related to the autoimmune system. Studies have found that some patients with premature ovarian failure often have a combination of autoimmune diseases such as Addison’s disease, hashimoto’s thyroiditis or rheumatoid disease. Strategies: If you suspect that a genetic or autoimmune disease is causing premature ovarian failure, you must go to a regular specialist hospital for early treatment to avoid missing the best treatment time. In addition, environmental pollution, staying up late, insomnia, smoking, alcohol consumption and multiple abortions are all risk factors for premature ovarian failure. In order to prevent POF, it is important to stay up less, not to diet, to exercise and lose weight, to exercise, to enhance physical fitness, to relax and to keep a happy mood. Also pay attention to diet, balanced diet and nutrition, choose soy products and other safe phytoestrogen supplementation dietary therapy. The actual fact is that you can find a lot of people who are not able to get a good deal on their own, but you can’t get a good deal on your own, so you can change your lifestyle and habits and start with the little things that you need to do to stay healthy and beautiful!