Chronic kidney disease patients will occur for many reasons, as follows: 1, doctors will let chronic kidney disease patients to adjust the diet structure, some patients worry that the onset of kidney disease progresses too quickly, may only consume a low-protein diet, so there is a certain impact on nutritional intake, so in the intake, such as the intake of protein, iron reduced, may lead to insufficient raw materials for hematopoiesis; 2, chronic kidney disease, especially to renal function failure, the patient because of renal failure led to a decrease in erythropoietin secretion, resulting in impaired erythropoiesis, that is, from infantile erythrocytes to mature erythrocytes, the need for erythropoietin, if there is no erythropoietin secretion, or reduce the amount of erythropoiesis will lead to reduced; 3, the patient in uremic conditions, renal failure, the internal environment is less conducive to the survival and growth of erythrocytes, resulting in The life span of red blood cells will be short, from generation to life span plus nutrition and other reasons, a combination of factors leading to less red blood cell production, more extinction. This is why patients with chronic kidney disease, especially those with end-stage renal failure, are often combined with renal anemia, a technical term for renal anemia, where the main problem is insufficient production and then possible increased destruction, leading to anemia.