Clinical manifestations of water retention in patients with chronic kidney disease combined with hypertension include persistently high blood pressure, puffiness of the eyelids and lower extremities, streaks of flame-like hemorrhage and cotton wool exudate in the retinal sclerosis fundus. Assessment methods include observation of cloudy urine, which is due to the fact that the kidney whose main function is to regulate the body’s acid-base, water and salt balance. When a person suffers from kidney disease, the human kidneys will not be able to eliminate salt and water adequately, which will produce water and sodium retention, resulting in reduced urination and cloudy urine. Observe for abnormal urination, such as less than 400ml of urine per day, or less than 100ml in the most severe cases, which can cause swelling of the eyelids and lower limbs in severe cases. Observe for blurred vision and blurred vision, as well as check the fundus of the eye for fundus lesions. Sclerosis of the arteries due to hypertension can be severe and lead to bleeding in the fundus.