Usually for asymptomatic gallbladder stones, no therapeutic measures are recommended, attention to regular annual physical examinations and regular abdominal ultrasound examinations are sufficient. Usually gallbladder stones require comprehensive assessment of the need for surgical treatment, and in most cases follow-up observation every six months, without prophylactic surgical removal. For gallbladder stones with symptoms or complications, laparoscopic cholecystectomy is the treatment of choice. In the acute phase, treatment of biliary colic, and in acute attacks combined with acute cholecystitis and other serious complications, the severity of the disease should be assessed before appropriate medication or surgery is given. Treatment of biliary colic can usually be treated with non-steroidal anti-inflammatory drugs, antispasmodics can be used, and opioids can be used for pain relief in severe symptoms, and morphine drugs are generally not recommended because they can aggravate biliary colic.