Midnight stomach pain, diarrhea, commonly due to the following points: 1, improper diet: consumption of spoiled and expired food, seafood, cold food, spicy and stimulating, pickled, fried, indigestible food, drinking alcohol and carbonated beverages, etc., should improve dietary habits, regular and balanced diet, avoid the intake of the above foods, quit smoking and alcohol. 2, bad habits: stay up late, irregular work and rest, mental stress, night 3, acute infection of the intestinal tract: can improve the stool examination plus occult blood, if necessary, stool culture plus drug sensitivity, blood tests, according to the results of diarrhea, the choice of antibiotics, rehydration, regulation of gastrointestinal flora and other treatment, such as montelukast, loperamide, cephalosporins or quinolones antibiotics, bifidobacterium Triptan capsules, etc., can be perfected colonoscopy.