Bile is a very complex solution. In the physiological state, various components of bile (bile acid salts, cholesterol, lecithin) are dissolved in bile, and it is only when the normal balance is altered or in some pathological state of the biliary system (e.g., infection) that insoluble components, precipitation, or stones occur. Due to the complexity of the gallstone disease, its causes are still inconclusive both at home and abroad. Gallbladder stones are associated with a variety of factors, and any factor that affects the altered ratio of cholesterol to bile acid concentration and causes bile stasis can lead to stone formation. It can be simply understood that after the bile is stagnant or concentrated, it is easy to form precipitates, and so on repeatedly over time, it forms insoluble stones. 1.Related to lifestyle habits. For example, patients who love to be still and do not like to move, and patients in late pregnancy, because of the reduction of physical activity, abdominal wall relaxation, visceral sagging, long-term compression of the bile ducts, so that the bile excretion is not smooth, the gallbladder muscle tension is reduced, resulting in the gradual accumulation of bile, concentration, deposition and formation of stones. According to relevant statistics, those whose weight exceeds the normal standard by more than 15% are 5 times more likely to suffer from gallstones than normal people. 2.Related to the chronic inflammation of the gallbladder. The gallbladder mucosa is stimulated by the concentrated bile or refluxed pancreatic juice and inflammation occurs, and its necrotic and detached mucosa and bacteria, viruses, etc. constitute a core, which promotes the deposition of cholesterol and bilirubin and the formation of stones over time. 3, cholesterol metabolic disorders: late pregnancy or postpartum women and high fat or patients, their blood cholesterol content is increased, the cholesterol content in the bile is also increased. At this time, if the bile is stagnant and the bile salt is reduced, it is very easy to form stones. 4, blind diet, no breakfast, sweet food, high-fat food and long-term use of certain drugs, such as Antoine, estrogen, etc., can lead to changes in the composition of bile. Bile is easily concentrated, cholesterol is saturated, and stones are formed by mutual deposition. British medical doctors found that more than 90% of gallstones patients have the habit of eating sweets. Another report a lot of dieting and no breakfast people, within four months, 1/3 of people suffer from stones. 5, post-operative gallbladder function is reduced, bile stagnation, the formation of stones over time. 6.People who have bad hygiene habits and infected with intestinal parasites. Roundworms that enter the bile duct or gallbladder can form stones after their death or eggs. 7, race, female hormones, obesity, pregnancy, high-fat diet, long-term parenteral nutrition, diabetes, hyperlipidemia, after gastrectomy or gastrointestinal anastomosis, terminal ileal disease and ileal resection, liver cirrhosis, hemolytic anemia and other factors can cause gallbladder stones. Health reminders: people who do not eat breakfast are more likely to get gallbladder stones, people in the morning fasting, bile in the gallbladder after about 12 hours of storage overnight, so that the saturation of cholesterol in the bile is higher. In the case of normal breakfast, due to the contraction of the gallbladder, the cholesterol is discharged with the bile, while the food stimulates the secretion of bile, resulting in a lower saturation of cholesterol in the remaining bile in the gallbladder, which makes the formation of stones less likely. If you don’t eat breakfast, due to the long fasting time, the bile in the gallbladder is stored for too long, resulting in the supersaturation of cholesterol in the bile, which in turn causes cholesterol deposits and gradually forms stones. Although the causes of gallbladder stones are very many, do not eat breakfast is a causal factor, but is very common, reasonable diet, regular life is a prerequisite for health.