Depression has a huge impact on the mental and physical health of menopausal women, directly affecting the quality of life and the length of life in later life, and has long attracted the attention of the medical community. Menopausal women, usually between 45-55 years old, are the core of the family, with the old and the young at the bottom, and when depression occurs, it not only affects their mood, but also the whole family. Because, as we know, emotions are contagious, if one person is unhappy, the whole family will be under a cloud and will be in pain. Menopausal depression generally starts slowly and develops gradually, beginning with symptoms of neurosis, such as insomnia, fatigue, dizziness, headache, irritability and other physical discomfort. Patients are often depressed, depressed, anxious, overly worried about accidents, remembering the past in a pessimistic and negative mood, comparing the present and worrying about the future. They think that they were young and successful in the past, but now they are more than half a century old, as if the sun is setting and they are approaching dusk, they are depressed, slow in thinking, slow in reaction, they feel that they are not energetic enough, they are not able to do their work, they are not interested in things they usually like, especially they are weak and easily fatigued, and they cannot be relieved even after rest. Irritability, inability to get in touch with others, often alone. When recalling the past unpleasant experiences, and when recalling some insignificant shortcomings and mistakes in the past, the patient often regrets, thinking that he has brought irreparable damage to the country and family, and now he should be punished and deserves to die. Patients believe that they are not only useless and hopeless, but also guilty, and some women will engage in self-injurious and suicidal behavior. Whether the suicide is successful or not, it will bring great pain to the family. In short, if you are at the age of menopause and feel uninterested in anything, depressed and frustrated, nervous and anxious all day long or do not suspect that you are suffering from an incurable disease, sometimes often suffering in one way or another, but no specific disease can be detected, it suggests that you may be suffering from menopausal depression. In this case, you should go to a specialist hospital for early and effective treatment.