There is a certain seasonality in depression, with a prevalence in spring and autumn. Depression is characterized by a significant and persistent depression, which is disproportionate to the person’s situation. It can range from depression to grief, and patients often complain that “there is no point in living” and “it’s hard to feel good”. Under the influence of depressed mood, patients have low self-esteem, feel inferior to others, and blame themselves for their own mistakes, feeling that they have caused problems to their families and society, often accompanied by self-blame and self-condemnation. Patients are unresponsive and feel that their brains are not turning. The patient’s behavior is slow, he or she is passive and lazy, and does not want to do anything. Patients with depression are often accompanied by somatic symptoms, such as sleep disturbances, fatigue, loss of appetite, weight loss, constipation, pain in any part of the body, loss of libido and various physical discomforts. Patients often go to non-psychiatry departments such as internal medicine, Chinese medicine and surgery without knowing it, which can easily lead to misdiagnosis or delayed treatment. Suggestions: Early recognition and acceptance of depression, and timely formal treatment. People tend to be afraid of depression, but in fact, depression is not terrible at all, it is treatable, preventable and controllable. In China, influenced by traditional culture, many people are reluctant to face and talk about mental problems, and even more reluctant to receive treatment. Domestic studies show that 92% of depressions do not seek treatment, and the identification rate of depression in non-specialized hospitals above the local and municipal level nationwide is less than 20%. Many patients think that once they are diagnosed with depression, it is like being put on the hat of mental illness, so they resist going to professional medical institutions for treatment. But in fact, these symptoms of depression are just like pneumonia, which can be difficult to control with fever, weakness, cough and phlegm, and also like pneumonia, which can be treated not only by taking good rest and drinking more water, but also by receiving anti-infection treatment in time, depression needs to receive antidepressant treatment in time, otherwise it may lead to The consequences can be undesirable. Eliminate concerns and receive antidepressant treatment. Many patients have many concerns about antidepressant treatment. One of the common concerns is the fear of drug side effects. Many patients like to read the drug instructions carefully or check various related contents on the Internet, but due to half-understanding, they may think that all the side effects written on the instructions, including even some rare reactions, may —- happen to them. In fact, many common side effects such as gastrointestinal reactions, headache side effects are only at the beginning of the treatment, generally adhere to a few days will slowly adapt to, to the drug began to play the role of antidepressants, a variety of side effects will reduce disappear. And just because there are some side effects of a certain drug does not mean that there will be side effects of another drug. It is especially important to note that many patients with depressive symptoms are mainly somatic discomfort and will be more sensitive to the original somatic discomfort at the beginning of the medication, which is not necessarily a side effect of the medication; establish a therapeutic alliance to fight depression together. The successful treatment of depression requires the joint efforts of many parties. Support and encouragement from family members, relatives and friends, correct understanding of treatment, and timely communication with doctors will make treatment more effective.