If a patient has headache symptoms, it is not possible to generalize what kind of medication is effective and has few side effects, but it is necessary to clarify the specific cause of the disease and use medication for it. Headache is mainly considered to be related to cold, migraine, tension headache, cerebrovascular disease and other diseases, which need to be treated by oral medication in combination with specific symptoms. 1. cold: due to viral infection of the upper respiratory tract, the toxins released affect local muscles and blood vessels, causing them to expand and spasm, resulting in headache symptoms in patients. At this time, antibacterial drugs, such as amoxicillin and cephalosporin, can be taken under the guidance of professional doctors. 2. Migraine: due to vasodilatation and contraction dysfunction, which causes patients to have headache symptoms. At this time, non-steroidal drugs can be taken to relieve symptoms, such as ibuprofen extended-release tablets and diclofenac sodium capsules, etc.; 3. Tension headache: due to long-term and continuous contraction of head and neck muscles, resulting in compression of small arteries and head ischemia, patients have headache symptoms. Non-steroidal and treprostatin drugs can be taken under the guidance of a doctor to relieve pain; 4. Cerebrovascular disease: cerebral hemorrhage, intracranial hematoma and other cerebrovascular diseases can also cause patients to have headache symptoms. Patients may have ruptured intracranial blood vessels, and after the blood overflows from the vessels, it trickles into the inside of the cranial cavity or the inside of the brain tissue, causing the pressure in the cranial cavity to rise, triggering headaches in patients. In this case, dehydration and cranial pressure-lowering drugs such as mannitol, glycerol fructose, furosemide, and human albumin can be applied for treatment. If explosion-like headache occurs and the situation is critical, prompt medical consultation is recommended to avoid delaying treatment. In addition to administering targeted medication, everyday patients can relieve head pain by taking hot baths, moderate exercise, adequate rest, and regular rest and relaxation.