Unpleasant headache is mainly considered to be related to cold, neurological headache, cranial tumor, cerebral hemorrhage and other diseases. Patients should clarify the causes through relevant examinations, and then take targeted treatment to relieve pain. In addition, patients are advised to get enough rest to promote recovery.1. Cold: Due to viral attack, the nervous system is easily stimulated, which in turn leads to uncomfortable headache. At this time, patients can take antiviral drugs for treatment under the guidance of a doctor. Adequate rest is recommended to relieve discomfort. 2. Neurological headache: Excessive tension and anxiety make the patient’s muscles contract, which in turn causes headache. At this time, patients should lie down and rest, and take non-steroidal drugs as prescribed by the doctor to relieve symptoms. In addition, patients can perform head massage or comb their hair to relax the head muscles to relieve pain. 3. Cranial tumor: Because brain tumor compresses the surrounding brain tissue and stimulates the meninges, it can cause headache. At this time, head CT and nuclear magnetic examination should be done to clarify the size, location and type of tumor, and then surgical resection should be performed. 4. Brain hemorrhage: due to the rupture of cerebral blood vessels and blood spillage, the blood pressure in the cranial cavity will change and the patient will have headache and other uncomfortable symptoms. At this time, the patient should be sent to the hospital immediately for dehydration and cranial pressure lowering treatment.