The pain caused by duodenal ulcers generally varies according to the severity and duration of the disease, and for duodenal ulcers with mild lesions the pain usually lasts about 3-5 days. After regular and reasonable drug application, such pain may gradually ease and gradually reach the level of complete disappearance. For more serious duodenal ulcers, including multiple ulcers or obvious bleeding ulcers, the pain may last for about 1-2 weeks, and patients often experience pain along with digestive symptoms, including nausea, vomiting and the possibility of vomiting blood and black stools. Therefore, it is important to pay high attention to the pain caused by such ulcers, to go to the hospital for gastroscopy in time to find the cause, and to provide systematic and standardized pain relief and symptomatic treatment for the cause.