Treatment of vegetative state to promote awakening Patients in vegetative state have a long time for treatment, rehabilitation or natural recovery. It has been reported that after thirteen years of home hospice, sitting, standing and wheelchair exercise for patients in vegetative state of gas poisoning, the patients finally regained consciousness and speech. There are also patients with traumatic brain injury coma who can walk and live on their own after more than one year of treatment and rehabilitation. There are also reports of patients with ischemic-hypoxic encephalopathy, hypoglycemic coma, and timely resuscitation from cardiac and respiratory arrest, who are able to go to work normally. The common feature of these real phenomena is basically that the rescue was timely and the effective time of treatment was seized. Of course, there are also those who need a longer period of adjustment and chronic treatment process due to the seriousness of the disease and the patient’s physical condition. Vegetative state patients treatment: 1, rehabilitation treatment: 2 hours of bedside sitting and standing in bed and 1 hour in wheelchair every day, regular training of limbs in the community into or hospital rehabilitation department, acupuncture, massage, foot bicycle, standing bed and other training. 2, drug treatment period: taking niacin tablets, blood circulation and stasis herbs, generally in October of each year to April of the next year treatment. Reduce the treatment in summer. Niacin and cerebral neurotrophic medication are given twice a year for one month each time.3. Application of human brain pacemakers: human brain pacemakers are divided into two types: DBS (deep electrical stimulation) and cervical medullary electrical stimulation. The current criteria for the selection of brain coma in China: ①Patients with traumatic brain injury, coma for more than 3 months, and patients with micro-consciousness are suitable for DBS. ②Patients in vegetative state, with brain atrophy and ventricular enlargement on brain imaging, who are not suitable for DBS, can choose cervical medullary electrical stimulation treatment. (③) Microconscious, those with the third ventricle transverse diameter less than 10mm on imaging can do DBS (deep electrical stimulation); those with the third ventricle transverse diameter more than 10-13mm on cranial CT film can choose cervical medullary electrical stimulation. ④Microconsciousness, young people, patients with ischemic-hypoxic encephalopathy and hypertonic coma are recommended to do DBS at 1 month. ⑤ The overall age window of patients in coma with DBS or SCS is 7-70 years.