So what kind of patients are suitable for spinal cord electrical stimulation implantation for wake-up surgery treatment? 1.Patients with severe craniocerebral trauma. 2.Large cerebral infarction, cerebral hemorrhage. 3. Ischemic-hypoxic encephalopathy. 4. Carbon monoxide poisoning. 5.Long-term coma caused by other reasons. When and under what conditions should a patient undergo surgery? If the patient is still in coma after 1-2 months after the acute period of traumatic brain injury, cerebral hemorrhage or other diseases, if the vital signs are stable, there is no inflammatory reaction and no fever, the patient can undergo “spinal cord electrostimulation coma and wake-up surgery”, and it is generally believed that early surgery is more effective than delayed surgery. What are the necessary tests that patients need to undergo before implantation surgery? 1. MRI (to understand the overall structure of the brain). 2.PETP-CT (to understand the metabolic situation of the brain). 3.Video EEG (to understand the electrophysiology of the brain and the activity of the cerebral cortex). 4.Evoked potential (to understand the excitatory connection of brainstem-thalamus-cortex). 5.Cerebrospinal fluid neurotransmitter detection (to understand the changes of neurotransmitters).