Television thoracoscopy was first used for the removal of large alveoli and for the treatment of spontaneous pneumothorax. TV thoracoscopy is even the best method to confirm the diagnosis of thoracic disease, and a pathological diagnosis is obtained by direct thoracoscopic biopsy. We often have to do pleural fixation when dealing with large pulmonary alveoli, which is done to prevent recurrence of the alveoli and production of pneumothorax. And pleural fixation keeps this possibility to a minimum. The best adhesive is sterilized talcum powder, but talcum powder has the potential to fibroticize or even malignantize the tissue and is now generally not used. Malignant pleural effusion is often produced by the metastasis of lung cancer or malignant tumor from other parts of the body to the pleura, characterized by large amount of bloody pleural fluid, repeated puncture to draw pleural fluid or put chest tube to drain, which is not easy to control and lose a lot of body fluid, leading to rapid failure and death of the patient, also affecting the quality of patient’s survival. Malignant tumors and pleural fluid often indicate advanced stage, with a median survival of 6 months, how to improve the quality of survival of patients have to prolong precious life? Thoracoscopic intrapleural spraying of sterile talcum powder is the best means to control malignant pleural fluid, but three conditions must be met: 1) whether the lung can be completely reopened, which is the first basis for pleural cavity adhesion. 2, fiberoptic bronchoscopy, trachea and bronchus must be open. 3, the tumor cannot be too large. 4.Age cannot be more than 75 years old, the effect is not good with age. 5, malignant pleural effusion with long time and large amount of effect is also not good. Malignant pleural effusion is the advanced stage of tumor, no matter how to treat it, it is impossible to achieve the curative result. TV thoracoscopic pleural endoprosthesis is only a means to prolong the survival period and improve the quality of survival, which cannot be expected too high. It is also a treatment for the family and doctors to do their last thought for the patient.