In thoracic surgery clinics, we often encounter patients complaining of chest pain without a clear history of trauma in their medical history. The thoracic surgeon will usually take a chest X-ray to exclude some causes that can lead to chest pain, such as pneumothorax, pleural effusion, pleurisy, pleural tumor, chest wall tumor, mediastinal tumor, and intrapulmonary lesions. If the chest X-ray can detect the problem and carry out targeted treatment, it can relieve the chest pain. However, in a considerable number of patients, chest radiographs show normal, and possible causes of chest pain at this time include costochondritis, intercostal neuralgia, chest wall myofasciitis, etc. Treatment for these causes mainly emphasizes symptomatic pain relief and can be topical topical or oral pain medication to relieve symptoms. It is worth noting that some non-thoracic diseases can also cause chest pain, such as angina pectoris in patients with coronary artery disease and herpes zoster in the chest, which should be promptly seen by the appropriate specialist.