1.Females with young age of first intercourse; 2.Females whose male sexual partners have cervical cancer sexual partners; 3.Females with multiple sexual partners or too frequent sexual intercourse; 4.Females who are receiving immunosuppressive therapy; 5.Females who smoke; 6.Females who have had cervical lesions, such as chronic cervicitis without timely treatment and history of malignant tumors in the reproductive tract; 7.Females with high-risk human papillomavirus infection in the reproductive tract Women with high-risk human papillomavirus infection of the genital tract; Wang Xiaoli, Department of Obstetrics and Gynecology, Chengdu Second People’s Hospital 8, women with current or previous herpes simplex virus infection; 9, women with HIV infection; 10, women with other sexually transmitted diseases, especially those with a mixture of sexually transmitted diseases.